受教育经历
2002/08-2006/01 美国纽约州立布法罗大学,交流障碍及科学系,临床听力学硕士,美国听力言语学会资格听力师
2002/08-2006/08 美国纽约州立布法罗大学,交流障碍及科学系,博士,导师:Richard J. Salvi教授
1993/07-1996/07 中国人民解放军总医院,耳鼻咽喉科,硕士,导师,李兴启教授
研究工作经历
2012/8 - 至今 美国纽约州立布法罗大学,交流障碍及科学系,副教授(associate professor)
2006/8 – 2012/8 美国纽约州立布法罗大学,交流障碍及科学系,助理教授(assistant professor)
1998/2 – 2002/8 美国纽约州立布法罗大学,听觉及耳聋中心,访问学者
1996/7 – 1998/2 中国人民解放军总医院,耳鼻咽喉科研究所,助理研究员
1991/7 – 1993/7 中国人民解放军总医院,耳鼻咽喉科研究所,助理工程师
主持或参加科研项目及人才基金项目情况
Tinnitus Research Consortium
The link between tinnitus and synaptic changes in the hippocampus
7/1/2011 – 6/30/2014, $300,000
The Royal National Institute for Deaf People (RNID, UK) (PI)
Auditory Cortex Reorganization Related to Tinnitus and Hyperacusis
10/1/2008-2/30/2013, $201,678
American Federation of Aging Foundation (AFAR) (PI)
How Presbycusis Affects Tinnitus
10/1/2008-9/30/2011, $59,775
NIH (R03) (PI)
Mechanism of Auditory Cortex Development and Role of NMDA Receptors
12/1/2006-11/30/2010, $237,750
National Organization of Hearing Research (PI)
Effects of Environmental Noise on Development in the Auditory Cortex
1/26/2007-4/30/2008, $20,000
UB2020 Interdisciplinary Research Development Fund (IRDF) (co-PI, PI Y., Yoon)
Micromachined Implantable Gradient Scaffold for Guided SGN Cell Culturing 7/1//2007-6/30/2008, $30,000
Deafness Research Foundation (PI)
Function changes of spiral ganglion neurons induced by hair cells loss
7/1/2005-6/30/2006, $20,000
National Organization of Hearing Research (PI)
Receptor plasticity of spiral ganglion neurons of cochlea
1/1/2005-12/31/2005, $15,000
American Tinnitus Association (PI)
Role of substance P and neurokinin receptor in tinnitus
6/1/2002 to 9/31/2003, $49,995
代表性论著:
1.* Zhang, C., Flowers E., Li, J., Wang, Q. and Sun, W. (2014) Loudness Perception Affected by High Doses of Salicylate – a Behavioral Model of Hyperacusis. Behavioral Brain Research 271C: 16-22. PMID: 24882611 (共同通讯作者)
2.* Sun, W., Fu, Q., Zhang, C., Manohar, S., Kumaraguru, A. and Li, J. (2014) Loudness perception affected by early age hearing loss. Hearing Research 313:18-25. PMID: 24747532 (通讯作者)
3.* Sun, W, Doolittle, L., Flowers E., Zhang, C. and Wang, Q. (2014) High Doses of Salicylate Causes Prepulse Facilitation of Onset-Gap Induced Acoustic Startle Response. Behavioral Brain Research 258: 187-192. PMID: 24149068 (通讯作者)
4.* Niu, Y., Kumaraguru, A., Wang, R. and Sun, W. * (2013) Hyperexcitability of inferior colliculus neurons caused by acute noise exposure. Journal of Neuroscience Research 91(2): 292-9 (通讯作者)
5.* Sun, W., Deng, A., Jayaram A. and Gibson B. (2012) Noise Exposure Enhances Auditory Cortex Response and Sound Loudness Perception. Brain Research 1458: 108-116 (通讯作者)
其他论著:
6.Guo, W., Yi, H., Ren, L., Chen, L., Zhao, L., Sun W. and Yang, S. (2014) The Morphology and the Electrophysiology of the Cochlea of the Miniature Pigs. Anat Rec (Hoboken) (DOI 10.1002/ar.23095).
7.Cai, Q., Whitecomb, B., Eggleston, J., Sun, W., Salvi, R. and Hu, B (2013) Round window closure affects cochlear responses to supra-threshold stimuli: Clinical implication for the diagnosis of round window atresia. Laryngoscope: PMID: 24114866
8.Chen, G., Stolzberg, D., Lobarinas, E., Sun, W., Ding, D. and Salvi, R. (2013) Behavioral and Physiological Manifestations of Salicylate Induced Tinnitus. Hearing Research 295: 100-113
9.Sun, W., Manohar, S., Jayaram, A., Kumaraguru1, A., Fu, Q., Li, L. and Allman, B. (2011) Early Age Conductive Hearing Loss Impairs Sound Perception Development. Hearing Research 282(1-2): 178-83 (通讯作者)
10.Lu, J., Lobarinas, E., Deng, A., Good, R., Salvi, R. and Sun, W. (2011) GABAergic Neural Activity Involved in Salicylate Induced Auditory Cortex Gain Enhancement. Neuroscience 189:187-98. PMID: 3153886 (通讯作者)
11.Sun, W., Tang, L. and Allman, B. (2011) Environmental Noise Delays Temporal Auditory Processing Development and Increases NMDA-2B Receptor Expression in Rat Auditory Cortex and Hippocampus. Behavioral Brain Research 218(1): 15-20. PMID: 3022098 (通讯作者)
12.Kraus K.S., Ding D., Jiang H., Lobarinas E, Sun, W. and Salvi, R.J. (2011) Relationship between noise-induced hearing-loss, persistent tinnitus and GAP-43 expression in the rat cochlear nucleus: Does synaptic plasticity in ventral cochlear nucleus suppress tinnitus? Neuroscience 194:309-325
13.Deng, A., Lu, J. and Sun, W. (2010) Temporal processing in the inferior colliculus and auditory cortex affected by high doses of salicylate. Brain Research 1344: 96-103. PMID: 20451503 (通讯作者)
14.Salvi R, Lobarinas E, and Sun W. (2010) Imaging Tinnitus Activity in the Brain. Perspectives on Hearing and Hearing Disorders: Research and Diagnostics, 14:21-27. PMID: 3136369
15.Wei, L., Ding, D., Sun, W., Xu-Friedman, M. and Salvi, J. (2010) Effects of sodium salicylate on spontaneous and evoked spike rate in the dorsal cochlear nucleus. Hearing Research267 (1-2): 54-60
16.Kraus, K.S., Mitra, S., Jimenez, Z., Hinduja, S., Ding, D., Jiang, H., Gray, L., Lobarinas, E., Sun, W., Salvi, R.J. (2010) Noise trauma suppresses neurogenesis in the rat hippocampus. Neuroscience 167: 1216-1226
17.Sun, W. and Salvi, R. (2009) BDNF and NT-3 modulate neurotransmitter receptor expressions on spiral ganglion neurons. Neuroscience164:1854-1866. PMID: 19778585 (通讯作者)
18.Salvi, R., Lobarinas, E. and Sun, W. (2009) Pharmacological treatments for tinnitus: new and old. Drugs of the Future 34(5):385-400. PMID: 20451503
19.Sun, W., Lu J., Stolzberg, D., Gray, L., Deng, A., Lobarinas E. and Salvi, R. (2009) Salicylate Increases the Gain of the Central Auditory System. Neuroscience 159: 325-334. PMID: 2759817 (通讯作者)
20.Sun, W., Hansen, A., Zhang, L., Lu L., Stolzberg, D. and Kraus, K.S. (2008) Neonatal nicotine exposure impairs auditory temporal processing development. Hearing Research 245(1-2): 58-64 (通讯作者)
21.Sun, W., Zhang, L., Lu, J., Yang, G., Laundrie, E. and Salvi, R. (2008) Noise exposure induced enhancement of auditory cortex response and changes in gene expression. Neuroscience 156:374-380. PMID: 2573047 (通讯作者)
22.Lobarinas, E., Sun, W., Stolzberg, D., Lu J. and Salvi, R. (2008) Animal model of tinnitus: behavioral results and preliminary physiological results from auditory cortex. Seminar in Hearing 29(4):333-349
23.Yang, G, Lobarinas, E., Zhang, L., Turner, J., Stolzberg, D., Salvi, R. and Sun, W. (2007) Salicylate Induced Tinnitus: Behavioral Measures and Neural Activity in Auditory Cortex of Awake Rats. Hearing Research 226(1-2):244-253. PMID: 16904853 (通讯作者)
24.Chen, L., Sun, W. and Salvi, R. (2006) Effects of nimodipine, an L-type calcium channel antagonist, on the chicken's cochlear potential. Hearing Research 221(1-2):82-90
25.Lobarinas, E., Yang, G., Sun, W., Ding, D., Mirza, N., Dalby-Brown, W., Hilczmayer, E., Fitzgerald, S., Zhang, L., Salvi, R.J. (2006) Salicylate and quinine induced tinnitus and effects of Memantine. ActaOtolaryngolSuppl. (556): 13-9.
26.Sun, W., Buzanska, L., Domanska-Janik, K., Stachowiak, M.K., Salvi, R.J. (2005) Voltage and ligand gated channels in differentiated fetal neural stem cells from the non-hematopoietic fraction of human umbilical cord blood. Stem Cells 23(7), 931-945. PMID: 16043459
27.Sun, W., Mercado III, E., Wang, P., Shan, X., Lee, T., Salvi, R.J. (2005) Changes in NMDA receptor expression in auditory cortex after learning. Neurosci Letters 374(1): 63-68.
28.Seigel, G.M., Sun, W., Wang, J., Hersberger, D.H., Campbell, L.M. and Salvi, R.J. (2004) Neuronal gene expression and function in the growth-stimulated R28 retinal precursor cell line. Current Eye Research 28 (4):257-269. PMID: 15259295
29.Sun, W., Ding, D., Wang, P., Sun, J., Jin, X., Salvi, R.J. (2004) Substance P Inhibits Potassium and Calcium Currents in Inner Ear Spiral Ganglion Neurons. Brain Research1012: 82-92.
30.Lobarinas, E., Sun, W., Cushing, R., Salvi, R.J. (2004). A novel behavioral paradigm for assessing tinnitus using schedule-induced polydipsia avoidance conditioning (SIP-AC). Hearing Research190:109-114.
31.Seigel, G.M., Sun, W., Salvi, R.J., Campbell, L.M., Sullivan, S.J., Reidy, J.J. (2003). Human corneal stem cells display functional neuronal properties. Molecular Vision9:159-63.
32.Sun, W., Seigel, G.M. and Salvi, R.J. (2002) Retinal precursor cells express functional ionotropic glutamate and GABA receptors. Neuroreport 13(8): 2421-2424.
33.Sun, W., Chen, L. and Salvi, R.J. (2002) Acoustical modulation of electrical evoked otoacoustic emission in chicken cochlea. Audiology & Neuro-Otology 7(4): 206-213.
34.Sun, W., Salvi, R.J.(2001) Dopamine modulates sodium currents in cochlear spiral ganglion neurons. Neuroreport 12(4). 803-807.
35.Chen, L., Sun, W. and Salvi, R.J. (2001). Electrically-evoked otoacoustic emissions from the chicken ear. Hearing Research. 161:54-64.
36.Reyes, S., Ding, D., Sun, W. and Salvi, R.J. (2001) Effect of inner hair cell lesions on electrically evoked otoacoustic emissions. Hearing Research. 158(1-2):139-150.
37.Sun, W., Ding, D., Reyes, S., Salvi, R.J. (2000) Effects of AC and DC stimulation on chinchilla SOAE amplitude and frequency. Hearing Research. 150(1): 137-148.
专著:所有作者,专著名称(章节标题),出版社, 总字数,出版年份.
1.Taggart, R.T., McFadden, S., Ding, D., Henderson, D., Sun, W. and Salvi, R.J. (2002) Gene expression changes in chinchilla cochlea from noise-induced temporary threshold shift. In D. Prasher, D. Henderson, Deepak Prasher, Richard Kopke, R.J., Salvi and Roger Hamernik, Noise Induced Hearing Loss: Basic Mechanisms, Prevention and Control. London. pp. 31-54
2.Salvi, R., Sun, W., Lobarinas, E. (2008) Anatomy and physiology of the peripheral auditory system. In: Roeser, R., Hosford-Dunn, H., Valente, M., (Eds.), Audiology Diagnosis. Thieme, New York. Pp. 17-36.
3.Salvi R, Lobarinas E, Sun W. (2009) Overview of Anatomy and Physiology of the Peripheral Auditory System.In: Chasin, M., (Ed.), Hearing Loss in Musicians: Prevention & Management. Plural Publishers, San Diego.
4.Allman, B.L., Sun, W., Kraus, K.S., Ding, D., Chen G.D., Stolzberg, D., Lobarinas, E., Salvi, R. (2010) Central auditory system neuroplasticity and hippocampal neurogenesis following cochlear insults. In: Salami, A., (Ed.), Neuroplasticity in the auditory brainstem: from physiology to the drug therapy. Nova Science Publishers, Hauppauge, NY.
5.Salvi, R., Lobarinas, E. and Sun, W. (2011) Behavioral Animal Models of Tinnitus, Pharmacology,and Treatment. In Molle: Textbook of Tinnitus. Springer
6.Sun, W. (2011) The Ion Channel of Cochlear Hair Cells, in Xingqi Li et al. Jianhe Sun, Shiming Yang and Qiuju Wang: Pathophysiology of the cochlea (Chinese)
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